Zhen Zhu An Shen Wan, meaning "Pearl Calming Pill," is a Traditional Chinese Medicine (TCM) formula designed to address sleep disturbances and mental unrest caused by Qi and Blood deficiency (气血双亏) .

The name comes from Zhen Zhu (pearl) , the key ingredient. In TCM, pearl has been used for centuries as a natural tranquillizer and sedative to calm the spirit (Shen) and protect the body's Yin . Historical texts, including the famous Compendium of Materia Medica, document pearl powder as a remedy for insomnia, palpitations, and stress-related disorders .

This formula is specifically indicated for a pattern called "Qi and Blood Deficiency" – a common condition in modern life caused by stress, poor diet, overwork, or chronic illness. When both Qi (vital energy) and Blood are deficient, the heart and mind lack nourishment, leading to restless sleep, palpitations, and mental fatigue .

You may benefit from Zhen Zhu An Shen Wan if you experience the following:

• Difficulty falling asleep or staying asleep, with restless, dream-disturbed sleep

• Waking up feeling tired, as if you did not rest

• Palpitations or a sensation of your heart racing, especially when tired or stressed

• Shortness of breath or feeling easily winded with minimal exertion

• Mental fatigue, poor concentration, or feeling "foggy"

• Lack of appetite or disinterest in food

• General weakness and low energy levels (fatigue)

• Pale complexion or pale tongue

• Feeling run down after illness or during recovery

In Traditional Chinese Medicine, this pattern is called "Qi and Blood Deficiency" (气血双亏). The heart houses the mind (Shen), and when the heart lacks sufficient Qi and Blood, the Shen becomes restless — manifesting as insomnia, palpitations, anxiety, and poor memory. This formula is traditionally used to replenish Qi, nourish Blood, and calm the Shen

Directions: 2 pills 2 times a day. Orally taken with warm water.

Medicinal Ingredients

Zhen Zhu (Tristania plicate) 7.2mg

Chuan xiong (Ligusticum sinense cv. chuanxiong) 4mg (5.4:1, QCE 21.6mg)

Fu ling (Wolfporia extensa) 0.32mg (67.5:1, QCE 21.6mg)

Bai shao (Paeonia lactiflora) 15mg (7.2:1, QCE 108mg)

Huang qi (Astragulus membranaceus) 4.7mg (4.6:1, QCE 21.6mg)

Chen pi (Citrus reticulata) 5.4mg (4:1, QCE 21.6mg) 

Hu po (Succinum) 21.6mg

San qi ( Panax notoginseng) 6.7mg (3.2:1, QCE 21.6mg)

Dang gui (Angelica sinensis) 7.55mg (2.9:1, QCE 21.6mg) 

Yuan zhi (Polygala tenufolia) 7.2mg 

Bai zhu (Atraclylodes macrocephala) 8.6mg (2.5:1, QCE 21.6mg) 

Sheng di huang (Rehmannia glutinosa) 9.7mg )2.2:1, QCE 21.6mg)

Liu shen qu (Massa medicate fermentata) 10.8mg 

Mu Li (Crassostrea gigas) 93.5mg 

Mu Li (Crassostrea gigas) 0.9mg (16:1, QCE 14.4mg) 

Non-medicinal Ingredients: Activated charcoal, Talc, Beeswax-White. No charcoal. No colorant. Natural color. 

Cauctions: If symptoms persist or worsen, or if you develop new symptoms, discontinue use and consult a health care practitioner. Do not use if you are pregnant or breast feeding. If you are taking prescription medications, consult a health care practitioner prior to use. If you have serious or major conditions, any type of acute infection, deficiency or excess, consult a health care practitioner prior to use. Do not use this product if you are taking thiazide diuretics, cardia glycosides, corticosteroids, stimulant laxatives or other medications which may aggravate electrolyte imbalance. Do not use if you have hypokalemia, high blood pressure, a kidney or cardiovascular disorder. Keep out of reach of children. Diuretic effect may occur. Do not use this product in cases of yin deficiency with heath signs, heat excess, or in the absence of significant Qi deficiency. Stop use if you experience insomnia, anxiety or headaches. Keep out of reach of children. Store protected from light and moisture. Security feature is self-evident.